Publications by authors named "S Gurofsky"
Furan is produced in foods during processing and preservation techniques that involve heat treatment. Previously, we reported that furan-exposed rats exhibited dose-dependent gross and histological changes in liver which correlated with changes in liver serum enzymes ALT, AST and ALP. Here we report the effects of furan on the male reproductive system.
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- Fumonisins B1 (FB1) and B2 (FB2) are toxic compounds from the Fusarium fungus, with FB1 usually present in higher amounts but both contributing to food and feed contamination.
- In a study with male rats, FB1 caused more severe clinical and hematological effects compared to FB2, impacting liver and kidney functions.
- Both toxins changed the expression of genes linked to the cell cycle, highlighting the need for more research into how FB1 and FB2 exert their toxic effects.
Male and female Sprague-Dawley rats were fed diets incorporating lyophilized chinook salmon obtained from Lake Ontario and Lake Huron. After 70 days, females were bred and the progeny (F1) were reared on the same fish-based diets as the adults (F0). After 78-133 days on the diets, males and females of both generations were sacrificed and hepatic microsomal enzyme activities determined, along with glutathione S-transferase-placental form (GSTP) expression and hepatic cellular proliferation.
View Article and Find Full Text PDFFluorescently labeled vinculin binds to focal contact areas in permeabilized cells independent of actin (Avnur, Z., J. V.
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