Publications by authors named "S Guler"
Introduction: Pneumonia is a common symptom of coronavirus disease-2019 (COVID-19), and this study aimed to determine how analyzing initial thoracic computerized-tomography (CT) scans using semi-quantitative methods could be used to predict the outcomes for hospitalized patients.
Materials And Methods: This study looked at previously collected data from adult patients who were hospitalized with a positive test for severe acute respiratory syndrome coronavirus-2 and had CT scans of their thorax at the time of presentation. The CT scans were evaluated for the extent of lung involvement using a semi-quantitative scoring system ranging from 0 to 72.
Background: Pulmonary rehabilitation (PR) aims to improve patients' functioning in interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD). The impact of change in functional independence during PR on subsequent survival has not been established. We aimed to determine functional independence during PR and its association with survival over three years post-PR.
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- The study investigates the relationship between language impairments and central auditory processing difficulties in children with self-limited epilepsy characterized by centrotemporal spikes, examining how these issues relate to seizure timing and neuropsychiatric aspects.
- Two groups of patients based on seizure timing underwent various assessments, revealing that both groups performed significantly worse on auditory processing tests compared to healthy controls, with some differences in expressive language scores.
- Findings indicate that children experiencing seizures at night may show more behavioral issues and impulsivity compared to those with seizures in the morning, highlighting the complex interactions between epilepsy, language, and neuropsychiatric functioning.
Effect of type of delivery and anesthesia method to ABR results on newborn hearing screening.
Int J Pediatr Otorhinolaryngol
December 2024
Objectives: The aim of this study is to examine the effect of type of delivery and anesthesia method on the screening ABR test results of newborns within the scope of the Newborn Hearing Screening Program (NHCP) and to investigate the relationship between the test results and the relevant variables.
Methods: 441 newborns were included in the study. Of these newborns, 221 constituted the control group (normal (vaginal) delivery), and 220 constituted the study group (cesarean section, delivery).
Article Synopsis
- The study aims to identify and validate transcriptomic signatures for various interstitial lung disease (ILD) subtypes, addressing the issue of limited sample sizes and lack of comparative studies between ILD types.
- Using patient-level data from 43 transcriptomics studies, the researchers developed classification models by integrating data from 1459 samples, resulting in robust transcriptomic signatures for conditions like idiopathic pulmonary fibrosis (IPF) and hypersensitivity pneumonitis (HP).
- This work represents the largest meta-analysis of fibrotic ILD transcriptomics, highlighting key gene expression trends that can help differentiate between ILD subtypes and link them to clinical outcomes like lung function deterioration.*