The role of kinetics, adsorption capacity, and heat and mass transfer effects in the sorption enhanced dimethyl ether synthesis (SEDMES) is investigated by means of a 2D+1D model of a single tube of an industrial-scale, externally cooled, multitubular reactor that simulates the reaction/adsorption step of the SEDMES cycle. The effect of the adsorbent/catalyst weight ratio is analyzed, showing that a trade-off between DME productivity and yield originates from the balance of kinetics and adsorption capacity in the reactor tube. The effects of internal diffusion in catalyst particles are shown to have a strong impact on effective reaction rates: significant yield/productivity improvements are obtained when using a mechanical mixture of catalysts with small particle diameters or by rearranging the distribution of the two active phases in hybrid or core@shell pellets.
View Article and Find Full Text PDFSudden Infant Death Syndrome (SIDS) is the term first proposed in 1969 for a distinctive subgroup of unexpected infant deaths occurring during the first months of life, with relatively consistent clinical, epidemiological and pathological features, which remain unexplained after a thorough case investigation, including a complete autopsy, examination of death scene and review of clinical history. Sudden infant death unnecessary means SIDS. According to definition, SIDS remains a diagnosis of exclusion, distinguished from others only by subjective and permissive variables.
View Article and Find Full Text PDFApnoea become a medical problem when associated with a symptomatology cohort characterized by skin colour modifications, muscular tone modifications and consciousness. This syndrome named ALTE, from the acronym Apparent Life Threatening Event, well describes the near death sensation in the witnesses. Only 60% of this events may be revealed in his etiopathogenesis, also even a strong diagnostic protocol is applied; the remaining part, called idiopathic represent a open doubt and stressing factor for the physicians.
View Article and Find Full Text PDFWe recently reported two cases of QT interval prolongation and cardiac arrest in newborns receiving antibiotic therapy with spiramycin, a macrolide agent extensively used for toxoplasmosis prophylaxis. In this study we assessed the effects of this drug on ventricular repolarization and on the potential risk of lethal arrhythmias in eight newborn infants in whom toxoplasmosis prophylaxis after birth was necessary. Electrocardiograms (ECGs) and echocardiograms were recorded during spiramycin therapy (350,000 i.
View Article and Find Full Text PDF