Resuming Training in High-Level Athletes After Mild COVID-19 Infection: A Multicenter Prospective Study (ASCCOVID-19).

Background: There is a paucity of data on cardiovascular sequelae of asymptomatic/mildly symptomatic SARS-Cov-2 infections (COVID).

Objectives: The aim of this prospective study was to characterize the cardiovascular sequelae of asymptomatic/mildly symptomatic COVID-19 among high/elite-level athletes.

Methods: 950 athletes (779 professional French National Rugby League (F-NRL) players; 171 student athletes) were included.

Mannan-induced Nos2 in macrophages enhances IL-17-driven psoriatic arthritis by innate lymphocytes.

Previous identification of the inducible nitric oxide synthase (NOS2) gene as a risk allele for psoriasis (Ps) and psoriatic arthritis (PsA) suggests a possible pathogenic role of nitric oxide (NO). Using a mouse model of mannan-induced Ps and PsA (MIP), where macrophages play a regulatory role by releasing reactive oxygen species (ROS), we found that NO was detectable before disease onset in mice, independent of a functional nicotinamide adenine dinucleotide phosphate oxidase 2 complex. MIP was suppressed by either deletion of or inhibition of NO synthases with NG-nitro-l-arginine methyl ester, demonstrating that Nos2-derived NO is pathogenic.

Chronic Active Arthritis Driven by Macrophages Without Involvement of T Cells: A Novel Experimental Model of Rheumatoid Arthritis.

Objective: To develop a new chronic rheumatoid arthritis model that is driven by the innate immune system.

Methods: Injection of a cocktail of 4 monoclonal antibodies against type II collagen, followed on days 5 and 60 by intraperitoneal injections of mannan (from Saccharomyces cerevisiae), was used to induce development of chronic arthritis in B10.Q mice.

Experimental Determination of the Thermal Diffusivity of α-Cryolite up to 810 K and Comparison with First Principles Predictions.

In aluminum electrolysis cells, a ledge of frozen electrolyte is formed on the sides. Controlling the side ledge thickness (a few centimeters) is essential to maintain a reasonable life span of the electrolysis cell, as the ledge acts as a protective layer against chemical attacks from the electrolyte bath used to dissolve alumina. The numerical modeling of the side ledge thickness, by using, for example, finite element analysis, requires some input data on the thermal transport properties of the side ledge.

Thermal conductivity of the sideledge in aluminium electrolysis cells: Experiments and numerical modelling.

During aluminium electrolysis, a ledge of frozen electrolytes is generally formed, attached to the sides of the cells. This ledge acts as a protective layer, preventing erosion and chemical attacks of both the electrolyte melt and the liquid aluminium on the side wall materials. The control of the sideledge thickness is thus essential in ensuring a reasonable lifetime for the cells.