Publications by authors named "S Guadarrama-Sistos Vazquez"

Background And Objective: Due to the potential debilitating sequelae following pediatric mTBI, the CDC published the Guideline on the Diagnosis and Management of mTBI Among Children in 2018. However, the guideline identified several key gaps in our clinical knowledge to support several clinical recommendations. The objective of this review is to evaluate if subsequent research has addressed these gaps in clinical practice recommendations.

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Background: The epidemiology of idiopathic pediatric epilepsy globally continues to be defined. To date there has been no evaluation of how national food availability may associate with the incidence and disability-adjusted life years (DALYs) lost from this condition. Correspondingly, the aim of this study was to define if such associations exist.

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Objective: Myelomeningocele (MMC) carries high morbidity and mortality. The Management of Myelomeningocele Study (MOMS) showed improved outcomes after prenatal compared to postnatal repair. However, it is unclear how the MOMS trial affected practice and outcomes in the Latin American region.

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Background: Bariatric surgery (BS) is the most effective intervention for severe obesity, leading to sustained weight loss, reduced obesity-related comorbidities, and cardiovascular mortality.

Aim: To assess changes in high-density lipoprotein (HDL) functions [cholesterol efflux capacity (CEC) and anti-inflammatory capacity] at different follow-up times in patients with severe obesity undergoing BS.

Methods: A prospective observational study within a cohort of consecutively enrolled patients with severe obesity scheduled to undergo BS.

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Article Synopsis
  • Anticoagulants like warfarin and direct oral anticoagulants (DOACs) are used to manage venous thromboembolism (VTE), particularly in obese patients, and recent guidelines on DOACs have been updated.
  • The study analyzed 1826 adult patients with obesity (BMI ≥30) and VTE from 2014 to 2022, focusing on the trends in DOAC prescriptions.
  • Results indicated a significant increase in DOAC prescriptions from 2017 to 2022, with over half of the patients receiving them, despite limited safety data for those with higher obesity levels.
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