Publications by authors named "S Grierson"

The last outbreak of classical swine fever (CSF) in the UK occurred in 2000. A total of 16 domestic pig holdings in the East Anglia region were confirmed as infected over a 3-month period. Obtaining viral genome sequences has since become easier and more cost-effective and has accordingly been applied to trace viral transmission events for a variety of viruses.

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Article Synopsis
  • In Europe, pigs are major carriers of Hepatitis E virus genotype 3 (HEV-3), which can infect humans through food consumption, although cooking reduces this risk.
  • A study on a farrow-to-finish pig farm showed high HEV prevalence in grower pigs (85.8%) compared to fatteners (26.0%), with HEV also detected in the farm environment, suggesting various sources of infection.
  • The research found that HEV was absent in piglet feces but first appeared at the weaner stage, particularly in mixed groups, highlighting the complexity of infection dynamics and the need for further investigation into control measures.
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Multidrug-resistant TB (MDR-TB) is a growing problem in the effort to end the global TB epidemic. In 2019, the WHO adopted a new standardised regiment for MDR-TB, consisting of only oral medications. We estimated the impact of the new guidelines on the costs of TB treatment in Estonia and Finland.

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In the United Kingdom, there has been an increase in the number of hepatitis E virus (HEV) infections in people annually since 2010. Most of these are thought to be indigenously acquired Orthohepevirus A genotype 3 (HEV G3), which has been linked to pork production and consumption. However, the dominant subgroup circulating in British pigs differs from that which is found in people; therefore, an alternative, potentially zoonotic, source is suspected as a possible cause of these infections.

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