Publications by authors named "S Grausova"

Article Synopsis
  • The study analyzed 65 cases of Escherichia coli bacteremia over seven years in a cancer hospital, focusing on risk factors, patient outcomes, and antibiotic susceptibility.
  • It found that E. coli was responsible for 20.8% of Gram-negative bacteremia, with a notable mortality rate of 17%, and identified major risk factors like solid tumors, prior surgeries, and recent chemotherapy.
  • The research indicated that monomicrobial E. coli bacteremia led to lower mortality rates compared to polymicrobial cases, while most E. coli strains remained susceptible to various antibiotics with minimal resistance observed during the study period.
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The risk factors, therapy and outcome of ten cases of fungemia due to Candida krusei, appearing during the last 10 years in a single national cancer institution, are analyzed. Univariate analyses did not find any specific risk factors in comparison to 51 Candida albicans fungemias appearing at the same institution and with a similar antibiotic policy. Association with prior fluconazole prophylaxis was not confirmed because only one case appeared in a patient previously treated with fluconazole.

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Three cases of Clavispora lusitaniae invasive fungal infections are reported. All three infections appeared in cancer patients presented with fungaemia, one additionally with meningitis. Two of them were breakthrough -- they developed during therapy with conventional amphotericin B with a dose of 0.

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