Publications by authors named "S Grama"
Burn injury represents a very important public health problem that affects all age groups. Of all burns, of particular interest is that of the perineum. Despite the importance of the subject, unfortunately, the medical literature on this anatomical region is sparse.
View Article and Find Full Text PDFThe management of severe burns is a complex process that requires a multidimensional approach to ensure optimal healing of burn wounds, minimize complications, and improve the prognosis of patients. Surgical debridement is considered the gold standard for removing necrotic tissue; however, this approach involves risks such as bleeding, the potential removal of viable tissue during excision, and technical challenges in complex anatomical areas. Recent advancements highlight the role of enzymatic debridement using NexoBrid, which offers a less invasive alternative to surgical excision while having the ability to selectively debride necrotic tissue and preserve viable tissue.
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- Burn injuries lead to serious trauma with high morbidity and mortality, making prompt management essential for improving patient outcomes, particularly focusing on biological parameters like thrombocytopenia.
- A two-year study of 90 severely burned patients revealed that thrombocytopenia was linked to a worse prognosis, as those with low platelet counts had higher mortality rates, especially in conjunction with other severe burn characteristics.
- The findings suggest thrombocytopenia can serve as an early warning sign for complications and may help predict outcomes in patients with severe burns, especially in those experiencing sepsis.
Burn patients manifest all components of Virchow's triad, amplifying the concern for venous thromboembolism (VTE). Routine prophylaxis for VTE remains a subject of debate, with the central concern being the occurrence of associated adverse events. We conducted a five-year retrospective study on burn patients admitted to our burn center.
View Article and Find Full Text PDFMetabolic-dysfunction-associated steatotic liver disease (MASLD) and metabolic syndrome (MetS) are inextricably linked conditions, both of which are experiencing an upward trend in prevalence, thereby exerting a substantial clinical and economic burden. The presence of MetS should prompt the search for metabolic-associated liver disease. Liver fibrosis is the main predictor of liver-related morbidity and mortality.
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