Publications by authors named "S Grafe"
Community-acquired respiratory viral infections (CARV) significantly impact patients with hematological malignancies (HM), leading to high morbidity and mortality. However, large-scale, real-world data on CARV in these patients is limited. This study analyzed data from the EPICOVIDEHA-EPIFLUEHA registry, focusing on patients with HM diagnosed with CARV during the 2023-2024 autumn-winter season.
View Article and Find Full Text PDFObjectives: The objective of this study is to examine the comparative effectiveness of vancomycin and metronidazole in a confirmatory analysis of event-free survival (EFS) after initial infection in patients with Clostridioides difficile from a German multicentre cohort study.
Methods: The IBIS multicentre cohort enrolled patients with an index episode of C. difficile infection between August 2017 and September 2020.
The formation of highly reactive singlet oxygen from alkaline superoxides presents an important reactivity of this component class. Investigations of the reaction paths such as disproportionation of LiO and NaO have been presented. Furthermore, the dissociation of these superoxide systems have been discussed as an alternative reaction channel that also allows the formation of singlet oxygen.
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- - This study explores how plasmon-driven reactions on silver nanoparticles are influenced by various factors, focusing on the protonation of 4-mercaptopyridine (4-MPY) in relation to binding modes and molecule interactions on the nanoparticle surface.
- - Two proton sources, molecular hydrogen and water, were evaluated, revealing that the binding mode significantly impacts the thermodynamics, kinetics, and light-driven charge-transfer directionality at the 4-MPY-Ag interface.
- - The research emphasizes the importance of electromagnetic field enhancement around the molecule, which doesn't alter the ground state thermodynamics but boosts light-driven charge-transfer and reactivity in plasmonic systems.
Serum prostate-specific antigen (PSA), its derivatives, and magnetic resonance tomography (MRI) lack sufficient specificity and sensitivity for the prediction of risk reclassification of prostate cancer (PCa) patients on active surveillance (AS). We investigated selected transcripts in urinary extracellular vesicles (uEV) from PCa patients on AS to predict PCa risk reclassification (defined by ISUP 1 with PSA > 10 ng/mL or ISUP 2-5 with any PSA level) in control biopsy. Before the control biopsy, urine samples were prospectively collected from 72 patients, of whom 43% were reclassified during AS.
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