Aim: This study aims to describe the social representations of breastfeeding among Mexican health science students.
Background: Breastfeeding is a complex phenomenon involving biological, affective and sociocultural aspects. Its definition includes diverse beliefs, attitudes, traditions and myths.
Importance: Combining immune checkpoint blockade (ICB) with chemotherapy improves outcomes in patients with metastatic gastric and gastroesophageal junction (G/GEJ) adenocarcinoma; however, whether this combination has activity in the perioperative setting remains unknown.
Objective: To evaluate the safety and preliminary activity of perioperative chemotherapy and ICB followed by maintenance ICB in resectable G/GEJ adenocarcinoma.
Design, Setting, And Participants: This investigator-initiated, multicenter, open-label, single-stage, phase 2 nonrandomized controlled trial screened 49 patients and enrolled 36 patients with resectable G/GEJ adenocarcinoma from February 10, 2017, to June 17, 2021, with a median (range) follow-up of 35.
In the context of climate change, extreme weather events and sudden shifts in weather patterns are becoming increasingly frequent. The atmosphere is considered a source of meteorological and climatic risks for human beings and living organisms. Numerous studies have examined the correlation between meteorological variables and human morbidity and mortality.
View Article and Find Full Text PDFMineral oil saturated (MOSH) and aromatic hydrocarbons (MOAH) and related hydrocarbons of synthetic origin are both packaging and processing contaminants of health concerns. The purpose of this work was to validate a method for their rapid and high-sensitivity determination in cocoa powder, using it to monitor the presence of these contaminants in products purchased in Italy and North Macedonia. Relevant primary and secondary packaging was also analyzed.
View Article and Find Full Text PDFLarge animal testing and clinical trials using bioengineered bladder for augmentation have revealed that large grafts fail due to insufficient blood supply. To address this critical issue, an in vivo staged implant strategy was developed and evaluated to create autologous, vascularized bioengineered bladder tissue with potential for clinical translation. Pig bladders were used to create acellular urinary bladder matrices (UBMs), which were implanted on the rectus abdominus muscles of rats and pigs to generate cellular and vascular grafts.
View Article and Find Full Text PDF