Publications by authors named "S Gomber"
Article Synopsis
- The study aimed to assess carotid intima media thickness (CIMT) and various metabolic parameters in children aged 7 to 12 years who are on anti-retroviral therapy (ART) for HIV, compared to healthy controls.
- Results showed that children with HIV had a significantly higher CIMT and increased body fat percentage, blood pressure, and cholesterol levels compared to controls.
- The findings suggest that HIV-positive children on ART experience notable metabolic abnormalities, highlighting the need for close monitoring of their cardiovascular health.
Background: Multi-drug resistance (MDR) in pediatric tuberculosis (TB) is a growing global threat. Unavailability of conventional or molecular drug susceptibility test (DST) in resource-limited settings often impede the determination of the extent of first line anti-tubercular drugs deployed in national programs.
Materials And Method: Pulmonary and extra pulmonary specimens were collected from clinically suspected pediatric TB cases, who were microbiologically confirmed.
Objective: To compare the long-term seroprotection (anti-HBs ≥10 IU/L) in children living with HIV (CLHIV) receiving a 3- or 4-dose double-strength (20 µg) recombinant Hepatitis B virus (rHBV) vaccination.
Methods: We present anti-retroviral therapy (ART) clinic based follow-up data collected from January, 2021 to August, 2022, from CLHIV who had received either 3-dose or 4-dose double-strength (20 µg) rHBV vaccination, after 36-42 months and assessed for anti-HBs titres, naïve and memory T-helper lymphocytes, CD4 counts and HIV viral load. Children found unprotected after primary immunization, were administered a single double-strength rHBV vaccine booster dose (20 µg) and seroprotection was reassessed after 4 and 12 weeks.
Article Synopsis
- The study investigates the impact of COVID-19 on patients with transfusion-dependent thalassemia (TDT) and compares their immune response to a control group without thalassemia.
- Symptomatic cases were less common among thalassemia patients, and while initial antibody levels were similar, thalassemia patients exhibited lower IgG levels over time.
- Severity of COVID-19 did not influence antibody titers, indicating that thalassemia patients generally experienced milder forms of the disease.
Article Synopsis
- - The study investigates COVID-19 antibody levels and disease severity in children who have received measles-rubella (MR) vaccinations compared to those who haven't, suggesting that vaccinations could influence outcomes.
- - Conducted with 90 COVID-19-positive children, the research measures antibody responses at different intervals, finding significantly higher COVID-19 antibody levels in vaccinated children without a notable difference in disease severity.
- - Results indicate that even a single dose of the MR vaccine boosts antibody response to COVID-19, but further randomized trials are needed to deepen understanding of this relationship.