Publications by authors named "S Gnanasekaran"

Background: Stevens-Johnson Syndrome (SJS) is an infrequent yet severe mucocutaneous reaction that involves less than 10% of the Body Surface Area (BSA). It is predominantly induced by certain medications, including anticonvulsants (e.g.

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Article Synopsis
  • - Menopause marks the end of menstrual cycles due to decreased reproductive hormone production, occurring after 12 months of no periods, and may be linked to an increased risk of Alzheimer's disease (AD) due to reduced estrogen levels.
  • - Estrogen is important for brain function, affecting energy use and cognitive abilities, and hormone replacement therapy (HRT) might offer cognitive benefits by enhancing estrogen's protective effects on the brain and improving heart health.
  • - While there’s a lot of evidence supporting estrogen's positive effects on brain health, clinical trial results on HRT's benefits for cognitive decline in menopausal women are inconsistent, highlighting the need for more research in this area.
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Despite global recognition, WHO reports reveal significant gaps, with one in four healthcare facilities lacking basic water services, affecting over 1.8 billion people, and 21% lacking sanitation services, impacting 1.5 billion people, especially prevalent in low- and middle-income countries.

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Background: Lower limb amputation can have profound physical, psychological, and social effects on individuals. Assistive aids like prosthetic lower limbs can help an individual regain mobility and thereby affect their self-esteem and quality of life.

Objective: To assess self-esteem and quality of life in patients with transtibial amputations who are using a transtibial prosthesis and explore the association between sociodemographic and amputation-related factors with self-esteem and prosthesis-related quality of life measures.

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Purpose: Functional endoscopic sinus surgery (FESS) is a mainstay surgical intervention for chronic rhinosinusitis with nasal polyposis (CRSwNP). Nasal irrigation, particularly with normal saline, is a widely recommended postoperative care modality. This systematic review and meta-analysis aimed to assess the efficacy of various nasal irrigation solutions in postoperative FESS patients.

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