Publications by authors named "S Glitho"

Background: Control of intermediate host snails using molluscicides for the control and/or elimination of schistosomiasis is a strategy in line with WHO recommendations. Niclosamide is the main chemical molluscicide recommended by WHO. However, except the immediate killing of the snail, the extent of the impact of the molluscicide application on the evolution of snail life-history traits, in relation to recolonization of treated sites is not well known.

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Background: Little attention has been devoted to the role of the immunoregulatory HLA-E/-F/-G genes in malaria. We evaluated the entire HLA-E/-F/-G variability in Beninese children highly exposed to Plasmodium falciparum (P.f.

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Aims: Schistosomiasis and malaria are endemic in sub-Saharan Africa where Schistosoma haematobium (Sh) and Plasmodium falciparum (Pf) coinfections are thus frequent. We explored the effect of Sh infection on antibody responses directed to Pf merozoite antigens and on malaria susceptibility in Beninese children.

Methods And Results: A total of 268 children were followed during a malaria transmission season.

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Article Synopsis
  • The study investigates the gene variability of HLA-G, HLA-E, and HLA-F in the Beninese Toffin population, highlighting their immunomodulatory roles and expression in the placenta.
  • Researchers found a total of 96, 37, and 68 variable sites in HLA-G, HLA-E, and HLA-F respectively, and identified different haplotypes for each gene.
  • The findings suggest that although the HLA-G/E/F alleles in the Toffin population are prevalent globally, their coding haplotypes are similar to those of other African populations, implying these genetic variations existed in Africa prior to the dispersion of humans.
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Hematologic diseases are a significant part of health disorders in Benin. As an example, anemia is the second cause of hospitalization, measuring up to 7.9% all over the country (National Plan of Sanitary Development, 2009-2018).

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