Publications by authors named "S Giubilato"

Article Synopsis
  • * Accurate assessment of LDL-C becomes challenging at low levels, so healthcare providers should consider other methods of measurement alongside different cholesterol parameters for better risk evaluation.
  • * Long-term studies suggest that low LDL-C levels generally don't lead to significant adverse effects, supporting the idea that intensive cholesterol-lowering treatments can be safely pursued to reduce cardiovascular risks.
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Takotsubo syndrome (TTS), also known as the broken-heart syndrome, is a reversible condition typically observed in female patients presenting for acute coronary syndromes (ACS). Despite its increasing incidence, TTS often remains undiagnosed due to its overlap with ACS. The pathophysiology of TTS is complex and involves factors such as coronary vasospasm, microcirculatory dysfunction, increased catecholamine levels, and overactivity of the sympathetic nervous system.

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Article Synopsis
  • * Managing AF effectively involves a multidisciplinary team (MDT), working closely with cardiologists and other healthcare providers to create a tailored care plan that addresses the complex nature of the disorder.
  • * Ongoing evaluation and adjustment of treatment are essential, as new risk factors, symptoms, and advancements in therapies can change the approach to AF management over time.
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Article Synopsis
  • * Treating AF in pregnant women is tricky since medications can pose risks to both mother and baby; thus, strategies like electrical cardioversion and beta-blockers are preferred for safety and effectiveness.
  • * Collaboration among healthcare professionals in a "Pregnancy-Heart Team" enhances patient care, but more research is necessary to establish the best treatment approaches for managing AF in pregnancy.
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Based on a wealth of evidence, aspirin is one of the cornerstones of secondary prevention of cardiovascular disease. However, despite several studies showing efficacy also in primary prevention, an unopposed excess risk of bleeding leading to a very thin safety margin is evident in subjects without a clear acute cardiovascular event. Overall, the variability in recommendations from different scientific societies for aspirin use in primary prevention is a classic example of failure of simple risk stratification models based on competing risks (atherothrombosis vs.

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