Publications by authors named "S Gipponi"
Introduction: The prognostic role of plasma neurofilament light chain (NfL), phospho-tau, beta-amyloid, and GFAP is still debated in Parkinson's disease (PD).
Methods: Plasma p-tau181, p-tau231, Aβ1-40, Aβ1-42, GFAP, and NfL were measured by SIMOA in 136 PD with 2.9 + 1.
We evaluated the impact of COVID-19 vaccination on disease outcome in hospitalized patients with SARS-CoV-2 infection with a prospective study. 745 vaccinated and 451 unvaccinated patients consecutively admitted to a COVID-19 Hospital from 1st September 2021 to 1st September 2022 were included. Compared with unvaccinated cases, vaccinated patients were older, had more comorbidities, but had a lower risk of O2 need (odds ratio, OR, 0.
View Article and Find Full Text PDFArticle Synopsis
- The study explores the impact of vaccination on the severity of COVID-19 in patients with neurological disorders, comparing outcomes between vaccinated and unvaccinated individuals admitted to a specialized unit.
- Among 232 hospitalized COVID-19 patients, 32% were fully vaccinated, with breakthrough cases being older and having higher comorbidity compared to unvaccinated patients, but similar disease progression and mortality rates.
- The analysis highlighted age and a specific early warning score as significant predictors of mortality, emphasizing the need to identify vulnerable neurological patients at greater risk during COVID-19 outbreaks.
Background And Purpose: The purpose of this study was to evaluate the possible correlation between SARS-CoV-2 vaccines and the onset of neurological syndromes. The aim was to challenge the association between SARS-CoV-2 vaccinations and the onset of acute functional neurological disorders (FNDs) compared to other neurological syndromes in hospitalized patients.
Methods: In this prospective cohort study, all adult inpatients consecutively admitted to a tertiary neurological centre were included.
Background And Objectives: A variety of neurologic disorders have been reported as presentations or complications of coronavirus disease 2019 (COVID-19) infection. The objective of this study was to determine their incidence dynamics and long-term functional outcome.
Methods: The Neuro-COVID Italy study was a multicenter, observational, cohort study with ambispective recruitment and prospective follow-up.