Publications by authors named "S Giovannoni"
Background: Neuroendocrine tumors (NETs), although rare, are considered one of the most common gastrointestinal and bronchopulmonary pediatric neoplasms. We aimed to determine the incidence, tumor characteristics, management, and outcome of NETs and explore the role of genetic predisposition, focusing on low and intermediate grade tumors.
Methods: Using the Danish National Pathology Registry, we conducted a nationwide retrospective study including all Danish children aged ≤18 years diagnosed with a pathology-proven NET between 1995 and 2020.
Article Synopsis
- A novel model simulating microbial processes in a 1 mL three-dimensional cube addresses gaps in existing ecosystem models by resolving individual microbes and their interactions at a 50 µm resolution.
- Key findings reveal that copiotrophic bacteria largely depend on eukaryotic phytoplankton for carbon, while oligotrophic bacteria rely on cyanobacterial exudates, highlighting distinct growth and substrate patterns in aquatic environments.
- The study also shows that attached bacteria lower carbon flux efficiency compared to free-living ones, indicating the importance of attachment and chemotaxis in optimizing bacteria's carbon acquisition in marine ecosystems.
Article Synopsis
- Vitamin B1 (thiamin) is essential for marine microorganisms, but many cannot synthesize it and must obtain it from their environment, particularly its pyrimidine precursor, HMP.
- HMP auxotrophy is common in marine plankton, and the low dissolved levels indicate that specialized uptake systems are needed to maintain these low concentrations.
- Research on the SAR11 clade, particularly Candidatus Pelagibacter st. HTCC7211, identified a sodium solute symporter called ThiV as the main transporter for HMP, with evidence showing its uptake is highly selective and regulated by environmental factors.
A hybrid organic monolithic column made of poly(lauryl methacrylate-co-1,6-hexanediol dimethacrylate) and the metal-organic framework MIL-68(Al) was prepared for the first time. The column was used in capillary liquid chromatography, both in isocratic and gradient elution modes. Separation performance towards small molecules of different chemical nature (polycyclic aromatic hydrocarbons, alkylbenzenes, phenols, etc.
View Article and Find Full Text PDFPassive sinking flux of particulate organic matter in the ocean plays a central role in the biological carbon pump and carbon export to the ocean's interior. Particle-associated microbes colonize particulate organic matter, producing "hotspots" of microbial activity. We evaluated variation in particle-associated microbial communities to 500 m depth across four different particle size fractions (0.
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