Publications by authors named "S Giannoni"
Many daily activities depend on visual inputs to improve motor accuracy and minimize errors. Reaching tasks present an ecological framework for examining these visuomotor interactions, but our comprehension of how different amounts of visual input affect motor outputs is still limited. The present study fills this gap, exploring how hand-related visual bias affects motor performance in a reaching task (to draw a line between two dots).
View Article and Find Full Text PDFMechanosensing and mechanotransduction pathways between the Extracellular Matrix (ECM) and cells form the essential crosstalk that regulates cell homeostasis, tissue development, morphology, maintenance, and function. Understanding these mechanisms involves creating an appropriate cell support that elicits signals to guide cellular functions. In this context, polymers can serve as ideal molecules for producing biomaterials designed to mimic the characteristics of the ECM, thereby triggering responsive mechanisms that closely resemble those induced by a natural physiological system.
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- The study investigated how acute ischemic stroke (AIS) affects patients with nonvalvular atrial fibrillation (NVAF) who are using oral anticoagulants (OA), specifically comparing direct oral anticoagulants (DOAC) and vitamin K antagonists (VKA).
- A total of 169 patients were examined, revealing that those on VKA had higher in-hospital mortality rates and poor outcomes 90 days after the stroke compared to DOAC users.
- The researchers found that switching anticoagulants did not impact stroke recurrence rates, suggesting that further extensive research is needed to optimize treatment for AIS in OA patients.
Article Synopsis
- Older age at onset and reduced dopamine binding in the caudate region are key risk factors for cognitive decline in Parkinson's disease (PD).
- A study of 128 drug-naive PD patients showed that baseline dopamine dysfunction correlates with cognitive performance and these factors can independently predict cognitive changes over 7 years.
- The research highlights that the caudate exhibits a greater age-related decline in dopamine binding compared to the putamen, suggesting a unique susceptibility in older PD patients to cognitive impairment.