Publications by authors named "S Giannakopoulos"
Müllerianosis of the urinary bladder is a rare pathological condition involving ectopic Müllerian-derived tissues within the bladder. Despite its benign nature, due to its ability to mimic malignant conditions such as bladder carcinoma, diagnosis might be challenging. In this review, data from 36 cases across 32 studies were analyzed, focusing on patient demographics, symptomatology, diagnostic imaging, and histopathological features.
View Article and Find Full Text PDFCompromised male reproductive health, including reduced testosterone and sperm count, is one of the long COVID symptoms in individuals recovering from mild-severe disease. COVID-19 patients display testicular injury in the acute stage and altered serum fertility markers in the recovery phase, however, long-term implications on the testis remain unknown. This study characterized the consequences of SARS-CoV-2 on testis function.
View Article and Find Full Text PDFArticle Synopsis
- The text discusses the diagnostic challenges of lesions in the urinary bladder, particularly focusing on endocervicosis, a rare condition characterized by benign infiltration of endocervical glands.
- It emphasizes the importance of thorough preoperative assessment for accurate diagnosis and highlights the potential association with adenocarcinoma, stressing the need for careful management.
- A case study of a 47-year-old woman illustrates the surgical approach of segmental cystectomy with tumor-only excision, which was confirmed as endocervicosis through histopathological analysis, showcasing the importance of tailored surgical interventions for better patient outcomes.
Article Synopsis
- Researchers developed a long COVID mouse model to explore neutrophil behavior during the recovery phase of COVID-19, filling gaps in knowledge due to the difficulty of studying human lung tissues.
- The study found that neutrophil recruitment and the formation of neutrophil extracellular traps remained active in the lungs for up to 30 days after infection.
- These neutrophil activities were linked to ongoing lung injury, including fibrosis and inflammation, indicating potential long-term effects of COVID-19 on lung health.
Article Synopsis
- Diagnostic ureteroscopy (dURS) is a valuable optional procedure for assessing patients with upper tract urothelial carcinoma (UTUC), particularly for obtaining tissue samples for histology.
- Data from the CROES-UTUC registry, analyzing 2380 patients, showed that dURS with biopsy was performed in 31.6% of cases, yielding adequate samples for diagnosis in 83.5% of situations, although about one-third of patients were under-staged.
- High-grade biopsies effectively predicted high-grade and high-risk diseases with high accuracy, but low-grade tumors showed a significant number of patients with undetected high-risk disease, indicating a need for better diagnostic methods.