Attenuation of receptor-dependent and -independent vasoconstriction in the human radial artery.

Background: Vasodilator strategies used to treat bypass grafts in the operating theatre, such as nitrates, phosphodiesterase inhibitors and calcium channel antagonists have a broad but short-lived effect against a variety of vasoconstrictor stimuli. Treatments that react irreversibly with proteins modulating vasoconstriction have the advantage that their effects can last well into the postoperative period. In addition systemic effects are avoided as the treatment is localised to the treated graft.

Cardiac surgery in patients with previous pneumonectomy.

Severe pulmonary dysfunction is a commonly occurring postoperative complication following cardiac surgery. Resection of a lung causes major anatomical and physiological changes. Shift of the mediastinum and reduction in respiratory function following pneumonectomy makes cardiac surgery challenging not only for the surgeon but also for the anaesthetist.

Use of transoesophageal echocardiography in management of penetrating cardiac injury.

A 53-year-old man who sustained an accidental cardiac nail gun injury presented to us in haemodynamically stable condition. He had an urgent plain radiograph film and contrast CT scan to determine the exact position of the nail. CT showed the nail to be in juxtacardiac position but did not give any conclusive information about breach of pericardium or myocardial wall.

Pleural inflammatory myofibroblastoma: a locally aggressive intra-thoracic tumour.

A 41-year old non-smoking woman presented with persistent pleural effusion. Pleural fluid was hemorrhagic and fluid cytology was negative for malignant cells. A working diagnosis of chronic haemothorax was made and standard right thoracotomy was performed to identify the source of bleeding.

Edge-to-edge technique for mitral valve repair: medium-term results with echocardiographic follow-up.

Background: The follow-up data for the Alfieri edge-to-edge technique of mitral valve repair is still a matter of interest. We describe the medium-term results of a single surgeon's practice with clinical and echocardiographic follow-up.

Methods: Between October 1998 and July 2003, 41 patients underwent the Alfieri repair.