Publications by authors named "S Ghezzo"
Objectives: To evaluate the quality of radiomics research in prostate MRI for the evaluation of prostate cancer (PCa) through the assessment of METhodological RadiomICs (METRICS) score, a new scoring tool recently introduced with the goal of fostering further improvement in radiomics and machine learning methodology.
Materials And Methods: A literature search was conducted from July 1st, 2019, to November 30th, 2023, to identify original investigations assessing MRI-based radiomics in the setting of PCa. Seven readers with varying expertise underwent a quality assessment using METRICS.
: PSMA PET radiomics is a promising tool for primary prostate cancer (PCa) characterisation. However, small single-centre studies and lack of external validation hinder definitive conclusions on the potential of PSMA PET radiomics in the initial workup of PCa. We aimed to validate a radiomics signature in a larger internal cohort and in an external cohort from a separate centre.
View Article and Find Full Text PDFOverall quality of radiomics research has been reported as low in literature, which constitutes a major challenge to improve. Consistent, transparent, and accurate reporting is critical, which can be accomplished with systematic use of reporting guidelines. The CheckList for EvaluAtion of Radiomics research (CLEAR) was previously developed to assist authors in reporting their radiomic research and to assist reviewers in their evaluation.
View Article and Find Full Text PDFArticle Synopsis
- This study examines the use of [Ga]Ga-DOTATOC PET radiomics to enhance the detection of lymph node metastases in patients with non-functioning pancreatic neuroendocrine tumors (NF-PanNET) prior to surgery.
- It involved 72 patients, analyzing various parameters such as sensitivity, specificity, and predictive values to assess the effectiveness of the imaging technique compared to traditional methods.
- The results show that radiomics improved sensitivity for detecting lymph node metastases from 24% to 77%, suggesting it could help clinicians better identify patients who may need more targeted surgical interventions.
Purpose: To compare the diagnostic accuracy and detection rates of PET/MRI with [Ga]Ga-PSMA-11 and [Ga]Ga-M2 in patients with biochemical recurrence of prostate cancer (PCa).
Methods: Sixty patients were enrolled in this prospective single-center phase II clinical trial from June 2020 to October 2022. Forty-four/60 completed all study examinations and were available at follow-up (median: 22.