Publications by authors named "S Gazzini"
Congenital meningoencephaloceles of the anterior skull base (ASB) are rare lesions that become evident during childhood and, if not properly diagnosed and treated, can be associated with severe complications. In the past, encephaloceles were treated exclusively with open surgical approaches, which, however, are associated with high complication rates. Recent years have seen the large-scale introduction of transnasal endoscopic approaches to the skull base, and several Authors suggest that endoscopic resection and repair in cases of meningoencephalocele may be the treatment of first choice, being associated with lower complication rates and reduced operative time compared with open procedures.
View Article and Find Full Text PDFVEGF as a Key Actor in Recurrent Respiratory Papillomatosis: A Narrative Review.
Curr Issues Mol Biol
July 2024
Article Synopsis
- Recurrent respiratory papillomatosis (RRP) is a condition caused by human papillomavirus (HPV) types 6 and 11 that leads to benign growths in the throat, especially affecting young kids who often face repeated episodes.
- Researchers have studied how HPV affects skin cells and can lead to serious diseases like cancer, but there’s also interest in how RRP works at a molecular level, including the role of blood vessel growth (angiogenesis) in the disease.
- A protein called VEGF helps with blood vessel growth and has led to the use of a treatment called bevacizumab, which shows promise in helping some RRP patients.
Objective: Atticotomy represents an essential surgical step within the management of attical cholesteatoma during endoscopic ear surgery. The aim of the present study was to evaluate the safety and functional results of an endoscopic atticotomy performed with piezosurgery, in terms of audiological outcomes and tissue's healing.
Methods: This is an observational retrospective study on patients with attical cholesteatoma who underwent endoscopic ear surgery with piezoelectric atticotomy and subsequent scutum reconstruction either with tragal cartilage or temporalis muscle fascia.