Publications by authors named "S Gautama"
Background: Cardiac troponin is commonly raised in patients presenting with malignancy. The prognostic significance of raised troponin in these patients is unclear.
Objectives: We sought to investigate the relation between troponin and mortality in a large, well characterised cohort of patients with a routinely measured troponin and a primary diagnosis of malignancy.
Article Synopsis
- - The study examined the relationship between peak pre-operative troponin levels and survival rates for patients undergoing coronary artery bypass grafting (CABG) after non-ST elevation myocardial infarction (NSTEMI), involving a cohort of 1,746 patients from five UK centers.
- - Results indicated that elevated troponin levels were a strong predictor of early survival (up to 30 days post-surgery) and demonstrated a significant interaction with the time taken to perform surgery; longer waits improved survival for patients with higher troponin readings.
- - The findings suggest that while troponin levels can guide the timing of surgery for improving immediate outcomes, they do not affect long-term survival beyond 30 days, highlighting their potential use
Background: A single dose strategy may be adequate to confer population level immunity and protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, especially in low- and middle-income countries where vaccine supply remains limited. We compared the effectiveness of a single dose strategy of the Oxford-AstraZeneca or Pfizer-BioNTech vaccines against SARS-CoV-2 infection across all age groups and over an extended follow-up period.
Methods: Individuals vaccinated in North-West London, UK, with either the first dose of the Oxford-AstraZeneca or Pfizer-BioNTech vaccines between January 12, 2021 and March 09, 2021, were matched to each other by demographic and clinical characteristics.
Article Synopsis
- A study analyzed data from over 13,000 patients with acute coronary syndrome (ACS) in the UK, focusing on those who experienced ventricular arrhythmias (VA) or cardiac arrest (CA) during their acute episode.
- The findings revealed that patients with VA or CA faced a significantly higher risk of future VA and that those who had CA also experienced a 36% increase in long-term mortality risk.
- This suggests that patients with VA or CA during ACS are at greater risk for ongoing heart rhythm issues and may need closer monitoring post-discharge.
Background: The successful implementation of clinical smartphone apps in hospital settings requires close collaboration with industry partners. A large-scale, hospital-wide implementation of a clinical mobile app for health care professionals developed in partnership with Google Health and academic partners was deployed on a bring-your-own-device basis using mobile device management at our UK academic hospital. As this was the first large-scale implementation of this type of innovation in the UK health system, important insights and lessons learned from the deployment may be useful to other organizations considering implementing similar technology in partnership with commercial companies.
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