Motor impairments caused by neurological diseases have an important impact on gait, particularly on the coordination between left and right lower limbs. Deviation from normal gait is often measured to assess this impact on gross motor functions, and to monitor the progress of patients during rehabilitation. The concept of gait dissimilarity map is introduced to represent bilateral raw gait signals, while accounting for their respective spatiotemporal dynamics.
View Article and Find Full Text PDFThis study addresses the characterization of normal gait and pathological deviations caused by neurological diseases. We focus on the angular knee kinematics in the sagittal plane and we propose to exploit Hidden Markov Models to build a statistical model of normal gait. Such model provides a log-likelihood score that quantifies gait quality.
View Article and Find Full Text PDFGait disorders in neurological diseases are frequently associated with spasticity. Intramuscular injection of Botulinum Toxin Type A (BTX-A) can be used to treat spasticity. Providing optimal treatment with the highest possible benefit-risk ratio is a crucial consideration.
View Article and Find Full Text PDFThis study addresses the characterization of normal gait and pathological deviations induced by neurological diseases, considering knee angular kinematics in the sagittal plane. We propose an unsupervised approach based on Dynamic Time Warping (DTW) to identify different normal gait profiles (NGPs) corresponding to real cycles representing the overall behavior of healthy subjects, instead of considering an average reference, as done in the literature. The obtained NGPs are then used to measure the deviations of pathological gait cycles from normal gait with DTW.
View Article and Find Full Text PDFWe propose a framework for optimizing personalized treatment outcomes for patients with neurological diseases. A typical consequence of such diseases is gait disorders, partially explained by command and muscle tone problems associated with spasticity. Intramuscular injection of botulinum toxin type A is a common treatment for spasticity.
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