Resuscitation in Paediatric Septic Shock Using Vitamin C and Hydrocortisone (RESPOND): The RESPOND Randomized Controlled Trial Protocol.

Objectives: Pediatric sepsis results in significant morbidity and mortality worldwide. There is an urgent need to investigate adjunctive therapies that can be administered early. We hypothesize that using vitamin C combined with hydrocortisone increases survival free of inotropes/vasopressors support until day 7 compared with standard care.

Posttraumatic hyperalgesia and associated peripheral sensitization after temporomandibular joint injury in mice.

Temporomandibular disorder (TMD) is the most prevalent painful condition in the craniofacial area. Recent studies have suggested that external or intrinsic trauma to the temporomandibular joint (TMJ) is associated with the onset of painful TMD in patients. Here, we investigated the effects of TMJ trauma through forced-mouth opening (FMO) in mice to determine pain behaviors and peripheral sensitization of trigeminal nociceptors in both sexes.

Partial or Focal Brachytherapy for Prostate Cancer: A Systematic Review and Meta-Analysis.

Introduction: Recent advances in image-guided brachytherapy have allowed for treatment volume reduction in the treatment of prostate cancer, with the aim to optimize disease control and reduce toxicities. This systematic review reports on the efficacy and safety of focal brachytherapy for treatment of patients with localized prostate cancer.

Methods: Medline, Embase, Web of Science and Cochrane were searched from inception to July 2023.

Follicular Lymphoma Presenting as a Primary Omental Mass: A Case Report and Pathological Analysis.

Follicular lymphoma (FL) is a gradually progressing type of B-cell non-Hodgkin lymphoma (NHL), distinguished by its characteristic follicular pattern of growth and a typically indolent clinical course. It is identified by the abnormal growth of B-cells in the lymph nodes. We report a case of a 45-year-old female who came up with complaints of heavy menstrual bleeding and easy fatiguability.