Publications by authors named "S Galluzzi"

Background: Developing interventions for older adults with subjective cognitive decline (SCD) has the potential to prevent dementia in this at-risk group. Preclinical models indicate that Citrus-derived phytochemicals could benefit cognition and inflammatory processes, but results from clinical trials are still preliminary. The aim of this study is to determine the effects of long-term supplementation with Citrus peel extract on cognitive performance and inflammation in individuals with SCD.

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Introduction: Remote monitoring technologies (RMTs) can measure cognitive and functional decline objectively at-home, and offer opportunities to measure passively and continuously, possibly improving sensitivity and reducing participant burden in clinical trials. However, there is skepticism that age and cognitive or functional impairment may render participants unable or unwilling to comply with complex RMT protocols. We therefore assessed the feasibility and usability of a complex RMT protocol in all syndromic stages of Alzheimer's disease and in healthy control participants.

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Background: The development of effective strategies to maintain good mental health of older adults is a public health priority. Mindfulness-based interventions have the potential to improve psychological well-being and cognitive functions of older adults, but little is known about the effect of such interventions when delivered through internet. During the COVID-19 pandemic we evaluated short- and long-term cognitive, psychological, and physiological effects of a mindfulness-based intervention (MBI) delivered via web-based videoconference in healthy older adults.

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Article Synopsis
  • Augmented reality (AR) apps can effectively differentiate between healthy individuals and those with early Alzheimer’s disease (AD) by measuring cognition needed for daily activities both in clinical and home environments.
  • The study found that the digital scores from the AR app were comparable or better than traditional cognitive scores in distinguishing stages of AD (preclinical and prodromal).
  • The app demonstrated good reliability with no learning effects noted, suggesting it is a promising tool for at-home cognitive assessment in individuals at risk for AD.
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