Publications by authors named "S Gales"

Article Synopsis
  • * This experiment produced 2.05 MJ of laser energy, resulting in 3.1 MJ of total fusion yield, which exceeds the Lawson criterion for ignition, demonstrating a key milestone in fusion research.
  • * The report details the advancements in target design, laser technology, and experimental methods that contributed to this historic achievement, validating over five decades of research in laboratory fusion.
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Bryconops Kner, 1858, includes two well defined subgenera based on morphological evidence, with each containing at least one species (B. (Bryconops) caudomaculatus and B. (Creatochanes) melanurus) with a very wide distribution, within which regional populations present color variations.

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Article Synopsis
  • Antitumor immunity can be weakened by immunosuppressive factors in tumors, particularly through the action of arginase-expressing cells that reduce l-arginine, crucial for T-cell and NK cell function.
  • AZD0011 is introduced as a new oral ARG inhibitor that, when used alone, can boost arginine levels, activate immune cells, and reduce tumor growth in various models.
  • Combining AZD0011 with anti-PD-L1 therapy enhances immune responses against tumors and shows promise in combination with other treatments like anti-NKG2A and type I IFN inducers, indicating potential for improved cancer immunotherapy strategies.
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Article Synopsis
  • * In inertially confined fusion, ignition allows the fusion process to spread into surrounding fuel, potentially leading to higher energy output.
  • * Recent experiments at the National Ignition Facility achieved capsule gains of 5.8 and approached ignition, even though "scientific breakeven" has not yet been fully realized.
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Background: Teleneurology for multiple sclerosis (MS) care was considered feasible, but utilization was limited.

Objective: To describe how the existing teleneurology populations at two academic MS Centers changed during the COVID-19 pandemic.

Methods: In this cross-sectional study, we captured all in-person and teleneurology visits at two academic MS Centers between January 2019 and April 2020.

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