Publications by authors named "S G Thrumurthy"
Article Synopsis
- The naked mole rat (NMR) is the longest-living rodent and offers insights into how evolution influences adult stem cell activity as lifespan increases.
- NMRs exhibit an increased number of intestinal Lgr5 stem cells, which divide more slowly than those in short-lived mice, yet have a similar turnover rate as human LGR5 cells.
- Instead of entering a resting state, these NMR stem cells slow their division by extending the arrest phase in their cell cycle and possess a higher ratio of differentiated cells that enhance intestinal protection and responsiveness to chemical changes.
Objective: Endoscopic resection (ER) often involves referral to tertiary centres with high volume practices. Lesions can be subject to prior manipulation and mischaracterisation of features required for accurate planning, leading to prolonged or cancelled procedures. As potential solutions, repeating diagnostic procedures is burdensome for services and patients, while even enriched written reports and still images provide insufficient information to plan ER.
View Article and Find Full Text PDFSurgery has a rich history, and in order to understand the various training pathways for aspiring surgeons one must have an appreciation of the evolution of surgery. This manuscript aims to deliver a brief review of the history of surgery, and explore the historical moments that have shaped the training pathway of surgeons in the United Kingdom (UK), and in doing so disseminate the latest information about surgical training in the UK.
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