Publications by authors named "S G Popova"

Background: Early life infections (ELIs), encompassing both viral and bacterial types, occur within the first six months of life. Influenced by genetic host factors and environmental conditions, the relationship between ELIs and subsequent allergic manifestations, particularly cow's milk protein allergy (CMPA) and atopic dermatitis (AD), is complex and not fully understood.

Objective: The aim of the current study was to examine the potential interplay between nutrition, infections, and allergic manifestations in the first six months of life in infants with a family history of allergies, who were either exclusively breastfed (EBF) or fed a combination of breast milk and standard (SF) or partially hydrolyzed infant formula (pHF).

View Article and Find Full Text PDF
Article Synopsis
  • Diagnostic accuracy in diagnosing Fetal Alcohol Spectrum Disorder (FASD) is under-researched, particularly in comparing different diagnostic criteria.
  • A systematic review identified six studies examining agreement rates between eight different FASD diagnostic criteria, revealing a range of agreement from 53.7% to 91% for individual children and 59.4% to 89.5% overall.
  • The study highlights significant variations in diagnostic outcomes and stresses the need for large-scale research to understand these discrepancies and their impact on clinical care.
View Article and Find Full Text PDF

Background: Data from birth registries can be studied to assess the prevalence of prenatal alcohol use and associated maternal and neonatal outcomes.

Methods: Linked maternal and neonatal data (2015-2018) for alcohol-exposed pregnancies were obtained from the Better Outcomes Registry and Network (BORN) Ontario. Descriptive statistics were generated for maternal demographics, prenatal substance use, mental health/substance use history, and neonatal outcomes.

View Article and Find Full Text PDF

The prevalence of fetal alcohol spectrum disorder (FASD) has been reported to be disproportionately high among children in foster care compared with the general population. However, updated prevalence estimates of infants and children with FASD in foster care or the prevalence of placement of children with FASD in foster care make this unclear. This study examines two questions.

View Article and Find Full Text PDF
Article Synopsis
  • Children and youths diagnosed with Fetal Alcohol Spectrum Disorders (FASD) at the Sunny Hill Centre in British Columbia, Canada, were studied, revealing a mean age of 9.7 years and an array of physical and mental health disorders linked to prenatal substance exposure.
  • Prenatal exposure to substances like cigarettes, cocaine, and opioids significantly increased the severity of FASD, with heightened odds of severe outcomes and involvement in the child welfare system.
  • Maternal mental health issues and poor nutrition further compounded the severity of FASD, emphasizing the need for screening of pregnant women for substance use, mental health, and nutritional status.
View Article and Find Full Text PDF