[Changes in the acid-base status of the synovial fluid in rheumatoid arthritis patients].

Aim: The study of changes in joint fluid (JF) acid-base balance in RA patients to evaluate severity of joint lesions, efficacy of on-going therapy and to predict appearance and persistence of RA remission.

Materials And Methods: A routine examination and measurements of JF pH of the affected joints and venous blood before and during the treatment were performed in 65 RA patients with articular or articular-visceral forms (46 and 19 patients, respectively). 19 patients were seropositive and 20 seronegative by rheumatoid factor.