[Antidepressant pharmacokinetics during pregnancy].

The influence of pregnancy state on the cytochrome P-450 dependent bioconversion and pharmacokinetics of antidepressants has been studied. Specific features of the bioconversion of some antidepressants are determined. Results of pharmacokinetic investigations based on the dynamics of antidepressant concentration in the blood plasma of pregnant women are considered.

[The position of individual nuclei of the midbrain of children and adolescents with respect to stereotaxic coordinates].

As demonstrate macromicroscopical and stereological investigations, performed on 147 brain preparations of children and adolescents, beginning from newborns up to 17 years of age, the substantia nigra and the nucleus ruber of the midbrain demonstrate flattened, spindle-like and spherical forms, respectively, which do not change with age. Their linear dimensions and stereotaxic coordinates increase with age from 1 to 3 mm. Individual anatomical variability of the nuclei in question is not connected with sex, side of the brain and form of the skull.