[Effect of serotonin on immune competent cells of biomodels under the conditions of vaccination against plague and tularemia].

Aim: Comparative evaluation of the effect of exogenic serotonin on the development of apoptosis and proliferative activity of immune system cells of biomodels in vivo and in vitro in the dynamic of immunity forming against plague and tularemia.

Materials And Methods: Analysis of relative content of immune competent cell DNA of unlinear and BALB/c mice was carried out after staining of the samples with mithramycin and ethidium bromide by flow cytometry.

Results: Administration of serotonin into biomodels before immunization with vaccine strains of Yersinia pestis and Francisella tularensis was established to increase in vivo proliferative activity of immune system cells, without a significant effect on their death by apoptosis.

[Modulating effect of serotonin on the development of human leukocytes apoptosis induced by Yersinia].

Effect of biogenic amine serotonin on the development of human blood leukocytes during interaction with species from Yersinia genus (Y. pestis EV, Y. pseudotuberculosis serovars I and IV, Y.

[The medical-and-genetic training of family physician].

The development of family medicine and promotion of genetic approaches to maintaining the health of population are under discussion in the paper. The necessity of training a new generation of physicians by using special programs is substantiated. The system approach to the training of family doctors must comprise, apart from clinical disciplines, the knowledge of human genetics as of a leading medical-and-biological branch of science.