Publications by authors named "S G Jiji"
Article Synopsis
- Silver nanoparticles (AgNPs) were eco-friendly synthesized using leaf extracts from both disease-susceptible red amaranthus and disease-resistant green genotypes, and were characterized using various scientific techniques.
- The nanoparticles showed effectiveness in inhibiting the mycelial growth of a specific plant pathogen at concentrations of 500 and 750 ppm, with notable differences in lesion development after treatment.
- Results indicated that AgNPs synthesized from disease-resistant amaranthus significantly reduced the incidence of leaf blight disease in susceptible plants, marking the first report on enhanced pathogen suppression using biogenically synthesized metal nanoparticles from disease-resistant plants.
In the present study, bacterial cellulose (BC) based nanocomposite dressing material was developed for third burn wound management by polydopamine (PD) coated BC with in situ reduction of silver nanoparticles (BC-PDAg). BC-PDAg nanocomposite was characterized to understand the morphological, physical and chemical properties. Antimicrobial activity of BC-PDAg against burn wound specific pathogens were significant.
View Article and Find Full Text PDFPyriproxyfen induced impairment of reproductive endocrine homeostasis and gonadal histopathology in zebrafish (Danio rerio) by altered expression of hypothalamus-pituitary-gonadal (HPG) axis genes.
Sci Total Environ
September 2020
Pyriproxyfen (PPF), a broad-spectrum insecticide known to cause reproductive and endocrine disruption in invertebrates, while the data is scarce in aquatic vertebrates. The goal of this study is to investigate the impact of PPF on reproductive endocrine system of male and female zebrafish along hypothalamus-pituitary-gonadal (HPG) axis. In brain, PPF caused significant alteration in the transcripts of erα, lhβ, and cyp19b genes in male and fshβ, lhβ, and cyp19b genes in female zebrafish.
View Article and Find Full Text PDFBacterial cellulose is well known for its excellent contributions in biomedical applications due to its superior properties. However the lack of antimicrobial property restricts its use in wound healing. To address the complications in third degree burns, thymol enriched bacterial cellulose hydrogel (BCT) was developed in this study.
View Article and Find Full Text PDFAims: Superparamagnetic iron oxide nanoparticles (SPIONs), as drug delivery vehicles, offer to eliminate the concerns associated with hydrophobic anti-cancer agents. The current study was intended to fabricate a SPION based delivery system for sorafenib that can simultaneously enable targeted delivery of sorafenib and expand its therapeutic index against hepatocellular carcinoma (HCC).
Main Methods: Co-precipitation and physical entrapment methods were employed for the synthesis of sorafenib loaded PVA coated SPIONs.