Publications by authors named "S G Glasgow"
Background & Aims: Perianal fistulizing Crohn's disease (PCD) is a common and debilitating complication with elusive pathophysiology. We examined mucosal cells from patients with PCD and related conditions using a multi-omics approach.
Methods: We recruited patients with PCD (n = 24), CD without perianal disease (NPCD, n = 10), and idiopathic perianal fistulas (IPF, n = 29).
Feasibility and outcomes of a trauma-informed model of care in residential treatment for substance use.
J Subst Use Addict Treat
November 2024
Article Synopsis
- - The study explored how a new trauma-informed care (TIC) model was implemented in a residential treatment center for young adults with substance use disorders (SUD) in Australia, evaluating its feasibility and impact on treatment outcomes.
- - Results showed that the TIC model was followed about 88% of the time, with nearly half of the clients completing the full treatment program, and significant reductions in substance use and improvements in mental health measures like depression and PTSD symptoms after three months.
- - Feedback from staff indicated that they felt capable and knowledgeable in delivering the TIC model, maintaining high professional quality of life throughout the study, which suggests that TIC is a promising approach for enhancing treatment effectiveness in residential settings.
Introduction: To examine and compare age groups on socio-demographic, substance use, mental health, social and risk behaviour profiles of people entering alcohol and other drug (AOD) treatment in a large non-government organisation (NGO) in Queensland and New South Wales, Australia.
Methods: Design-Cross-sectional study; analysis of baseline routine outcome measures (ROM) and AOD minimum datasets for drug and alcohol treatment services. Setting and participants-People enrolling in Lives Lived Well, a large NGO AOD service between November 2020 and October 2022.
Neural circuits governing all motor behaviors in vertebrates rely on the proper development of motor neurons and their precise targeting of limb muscles. Transcription factors are essential for motor neuron development, regulating their specification, migration, and axonal targeting. While transcriptional regulation of the early stages of motor neuron specification is well-established, much less is known about the role of transcription factors in the later stages of maturation and terminal arborization.
View Article and Find Full Text PDFBackground: Chronic idiopathic constipation (CIC) is a substantial problem in pediatric and adult patients with similar symptoms and workup; however, surgical management of these populations differs. We systematically reviewed the trends and outcomes in the surgical management of CIC in pediatric and adult populations.
Methods: A literature search was performed using Ovid MEDLINE, Embase, Scopus, the Cochrane Central Register of Controlled Trials, and ClinicalTrials.