[Mosaicism of the upper respiratory tract epithelium in liquidators of the Chernobyl accident].

On the basis of findings from the structural analysis of 21 nasal mucosa biopsy specimens of patients with chronic rhinitis including 12 participants in liquidation of the consequences of the Chernobyl accident using morphometric methods, signs of morphofunctional insufficiency of the nasal epithelium are verified. Mechanisms of this phenomenon development are discussed.

[The structural changes in the lungs in the acute period of a myocardial infarct in the wake of ventricular fibrillation].

Time-related course was studied of structural changes in the lung tissue in acute myocardial infarction having developed in the wake of secondary ventricular fibrillation, using investigational methods common in biology, histochemistry, and electron-microscopy. It has been found out that development in patients with acute myocardial infarction of ventricular fibrillation greatly aggravates the course of the illness inducing origination of profound and even irreversible alternative changes in all constituents of the aerohematic barrier. The above patients developed structural as well as functional pulmonary insufficiency which is at its greatest within 2 to 4 days of the onset of ventricular fibrillation.

[The mechanism of the development of a fat microembolism in myocardial infarct].

It was found out with the aid of morphological methods that during the acute phase of myocardial infarction there develops fat embolism of the vascular bed of not only pulmonary circulation but also systemic circulation. One of the sources of fat embolism is the degenerated myocardium: during the process of its contraction fat drops move out of the cardiomyocytes and may penetrate into the capillary network.

[Lipid metabolic changes in the lung tissue of patients dying in the acute period of a myocardial infarct].

Fatty-acid composition of lipids was determined as was activity of lipid peroxidation and lung tissue content of neutral fats and phospholipids in myocardial infarction during the acute phase of the course of the disease using gas-chromatographic, biochemical, and morphological techniques. Lung tissue in myocardial infarction was found out to accumulate neutral fats. Also recordable in lung tissue was redistribution of phospholipids, with the interalveolar septa structures getting reduced, which fact is accompanied by changes in fatty acid composition of lipids together with activation of lipid peroxidation processes.