Publications by authors named "S G Fukuchi"
Article Synopsis
- EUS-guided biliary drainage (EUS-BD) has shown good results in high-volume centers, but this study investigates its safety and effectiveness in newer centers that recently adopted the procedure.
- The research involved 22 centers from 2017 to 2022, assessing 255 patients and looking at the success and complications of EUS-BD performed by 84 endoscopists.
- The study found a high technical success rate of 91.4% but identified specific risks for failure and complications, including smaller puncture target diameters and moderate ascites, highlighting that the experience level of endoscopists did not significantly affect outcomes.
Objective: Despite the benefits of anterior temporal lobectomy with amygdalohippocampectomy in patients with temporal lobe epilepsy (TLE), approximately up to 5% may have hemiparesis as its postoperative complication. This paper aims to describe which step/s of the anterior temporal lobectomy with amygdalohippocampectomy have the highest probability of having the greatest decrease in motor evoked potential (MEP) amplitude.
Methods: This study used a cross-sectional design of obtaining data from TLE patients who underwent anterior temporal lobectomy with amygdalohippocampectomy with transcranial MEP monitoring.
Article Synopsis
- The study investigates cell-cell interactions in colorectal cancer (CRC) to understand how adenomas progress to sporadic CRC, aiming to improve patient survival rates.
- By using spatial transcriptomics on early and advanced CRC cases, the researchers identified key interactions between cancer cells and regulatory T cells (Tregs) that may lead to immune suppression in the tumor microenvironment.
- Findings highlight midkine (MDK) as a critical signaling molecule involved in these interactions and indicate that higher MDK/SDC4 levels are linked to poorer survival outcomes in CRC patients, suggesting a potential target for early diagnosis and treatment.
A 65-year-old woman presented with a flat elevated lesion of about 1cm in the cecal diverticulum during a lower gastrointestinal endoscopy that was performed previously by another physician during a medical checkup. The patient was referred to our department for resection. Considering the risk of perforation owing to the diverticular lesion, positive nonlifting sign, and Group 5 diagnosis on the previous biopsy, EMR with over-the-scope clip (OTSC) (EMRO) was selected, and complete resection was achieved without complications.
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- EUS-BD (endoscopic ultrasound-guided biliary drainage) is now seen as a top choice for certain biliary obstructions, similar to retrograde cholangiopancreatography.
- The study analyzed various experience-related factors at beginner hospitals to assess their impact on EUS-BD outcomes, comparing successful cases to those that failed.
- Key findings indicated that meeting certain experience thresholds for institutions and operators (like a minimum number of procedures performed) was linked to better success rates in EUS-BD interventions.