Publications by authors named "S G Chamberlin"

Article Synopsis
  • - The study assessed the effectiveness of a portable autorefractor, QuickSee Free (QSF), in detecting refractive errors in school-aged children in The Gambia, comparing it to a standard eye examination method (cycloplegic retinoscopy).
  • - Involving 101 children, the results showed that the QSF had moderate correlation with physician measurements for spherical equivalent, sphere, and cylinder values but typically underestimated these measures.
  • - Sensitivity and specificity rates indicated that QSF was fairly accurate at detecting myopia, anisometropia, and astigmatism, demonstrating good predictive ability according to the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) guidelines.
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Background: A water extract of the Ayurvedic plant (CAW) improves cognitive function in mouse models of aging and Alzheimer's disease, and affects dendritic arborization, mitochondrial activity and oxidative stress in mouse primary neurons. Triterpenes (TT) and caffeoylquinic acids (CQA) are constituents associated with these bioactivities of CAW although little is known about how interactions between these compounds contribute to the plant's therapeutic benefit.

Methods: Mouse primary cortical neurons were treated with CAW, or equivalent concentrations of four TT combined, eight CQA combined, or these twelve compounds combined (TTCQA).

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Background: Lung cancer is the leading cause of cancer death in the United States. Lung cancer screening (LCS) decreases lung cancer mortality. Emergency department (ED) patients are at disproportionately high risk for lung cancer.

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Article Synopsis
  • Coronavirus can lead to serious health issues, exemplified by SARS-CoV, MERS-CoV, and SARS-CoV-2 outbreaks, indicating significant variation in disease outcomes among infected individuals.
  • Researchers are using mouse models and human genetic studies to identify gene locations that influence how these coronaviruses affect infection severity and replication.
  • Their findings highlight specific genes that may play roles in virus response, offering insights for future research on how to combat similar viruses that jump from animals to humans.
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