Publications by authors named "S G Besser"

Background: The benefit of pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF) and heart failure with reduced ejection fraction (HFrEF) is well established; its efficacy in patients with heart failure preserved ejection fraction (HFpEF) is less clear.

Objective: The objective of the study was to compare AF and heart failure (HF) rehospitalizations after PVI in patients with HFpEF vs HFrEF.

Methods: The IBM MarketScan Database was used to identify patients undergoing PVI for AF.

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Article Synopsis
  • Diabetes mellitus (DM) and elevated lipoprotein(a) [Lp(a)] are both significant predictors of coronary artery disease (CAD) outcomes, but their combined effects are not well understood.
  • A study analyzing data from over 6,200 patients found that those with either condition had higher rates of cardiovascular death or myocardial infarction (MI), especially those with elevated Lp(a).
  • Elevated Lp(a) was shown to be an independent risk factor for CAD outcomes, increasing risk for patients with or without DM.
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Background: Lipoprotein (a) [Lp(a)] is a robust predictor of coronary heart disease outcomes, with targeted therapies currently under investigation. We aimed to evaluate the association of high Lp(a) with standard modifiable risk factors (SMuRFs) for incident first acute myocardial infarction (AMI).

Methods And Results: This retrospective study used the Mass General Brigham Lp(a) Registry, which included patients aged ≥18 years with an Lp(a) measurement between 2000 and 2019.

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Background: Cardiogenic shock (CS) is complicated by high mortality rates. Targeted temperature control (TTC) has been proposed as an adjunct therapy in CS. This study aims to examine the safety of TTC in patients presenting with CS.

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