The Aryl Hydrocarbon Receptor (AhR) Is a Novel Gene Involved in Proper Physiological Functions of Pancreatic β-Cells.

The Kynurenine pathway is crucial in metabolizing dietary tryptophan into bioactive compounds known as kynurenines, which have been linked to glucose homeostasis. The aryl hydrocarbon receptor (AhR) has recently emerged as the endogenous receptor for the kynurenine metabolite, kynurenic acid (KYNA). However, the specific role of AhR in pancreatic β-cells remains largely unexplored.

Phase transformation and metallurgical characterization of heat-treated nickel-titanium rotary instruments using differential scanning calorimetry, X-ray diffraction, and energy dispersive spectrometry.

Objective: The present study aimed to evaluate the phase transformation behavior and elemental analysis of thermomechanical-treated nickel-titanium (NiTi) rotary instruments, TruNatomy (Dentsply Sirona), HyFlex CM (coltene, Whaledent), and Neoendo Flex (Orikam healthcare India), using differential scanning calorimetry (DSC), X-ray diffraction (XRD), and energy dispersive X-ray spectrometry.

Materials And Methods: A total of 18 NiTi rotary instruments, TruNatomy, Hyflex CM, Neoendo Flex, taper. 04, size 25 (except TruNatomy, size 26) were selected and were divided into three groups ( = 6).

Occult Breast Cancer in High-Risk Gene-Positive Pakistani Women Undergoing Contralateral Prophylactic Mastectomy/Prophylactic Mastectomy: Implications for Sentinel Lymph Node Biopsy.

Introduction: Sentinel lymph node biopsy (SLNB) of the axilla is standard in breast cancer (BC) management; however, its role in prophylactic/contralateral prophylactic mastectomy (CPM) is still questioned. To avoid future consequences on surgical morbidity and socioeconomic aspects in low and middle-income countries (LMICs), we intend to determine the prevalence of occult breast cancer (OBC) among CPM cases.

Objective: To determine the prevalence of OBC in patients undergoing prophylactic mastectomy (PM).

Pymetrozine induced remarkable hemato-biochemical modifications and genotoxicity in vital organs of bighead carp ().

Pymetrozine (a pyridine azomethine pesticide) is one of the most commonly and frequently used insecticides. Scanty information is available about the deleterious effects of Pymetrozine on fish especially bighead carp. Hence, the current study investigated chronic toxicological effects of pymetrozine in bighead carp.

Impact of rhizobacterial inoculation in plant growth medium to mitigate lead stress in Tomato (Solanum lycopersicum L.).

This study investigates the effects of lead stress on tomato plants and explores the potential role of plant growth-promoting rhizobacteria (PGPR) to alleviate this stress. The experiment was conducted in pots, introducing varying lead levels (0, 100, 200, 300, 400, and 500 mg kg⁻¹) using lead nitrate. For rhizobacterial inoculation, pre-characterized LTPGP strains S5 Pseudomonas fluorescens A506 and S10 Pseudomonas fluorescens LMG 2189 were used.