Publications by authors named "S Furudoi"
Article Synopsis
- The study aimed to develop guidelines for antibiotic use during tooth extractions in cancer patients on denosumab, as there's a risk of medication-related osteonecrosis of the jaw (MRONJ).
- It analyzed 68 cancer patients' antibiotic administration practices and their correlation with MRONJ after tooth extractions over a 10-year period.
- Results showed a lot of inconsistency in antibiotic usage among hospitals, with amoxicillin being the most common; however, no significant link between MRONJ occurrence and the dosage or duration of amoxicillin was identified, suggesting a single preoperative dose may be sufficient.
Effect of Statins on Patients With Osteoradionecrosis of the Jaw.
J Oral Maxillofac Surg
December 2024
Background: Osteoradionecrosis of the jaw (ORN) is a late complication of radiation therapy. Radiation-induced fibrosis is the most likely mechanism for developing ORN, and statins are effective against radiation-induced fibrosis. However, no reports have indicated the direct effectiveness of statins in treating ORN.
View Article and Find Full Text PDFBackground/purpose: The incidence of medication-related osteonecrosis of the jaw is increasing worldwide, mostly due to the use of antiresorptive agents (ARAs) such as bisphosphonate (BP) and denosumab (Dmab). However, the proportion of BP-related osteonecrosis of the jaw (BRONJ) and Dmab-related osteonecrosis of the jaw (DRONJ) among all ARA-related osteonecrosis of the jaw (ARONJ) cases is not clear; this hinders appropriate treatment, recurrence-prevention planning, and avoidance of unnecessary Dmab withdrawal. Moreover, the causative drug administered at each disease stage remains unknown.
View Article and Find Full Text PDFArticle Synopsis
- Necrotizing fasciitis (NF) in the oro-cervical region is rare and not well understood, prompting a study to compare its characteristics with severe cellulitis and NF in other body areas.
- The study analyzed risk factors for oro-cervical NF (OCNF) using various indicators like the neutrophil-to-lymphocyte ratio (NLR) and Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score, finding that higher NLR and LRINEC scores are linked to OCNF prevalence.
- Results indicated that while OCNF patients had higher inflammatory markers than those with NF in other regions, they also had lower clinical stages and mortality rates, suggesting these indices
We report here a case of mandibular osteomyelitis in a 63-year-old female in which quantitative values determined using bone SPECT/CT were useful to evaluate response to antibiotic therapy, hyperbaric oxygen therapy, and sequestomy. After finishing therapy, the chief complaints were well relieved, and posttreatment Tc-99m HMDP bone SPECT/CT examination showed decreased uptake. The maximum standardized uptake value (SUV), peak SUV, mean SUV, metabolic bone volume, and total bone uptake of the untreated lesion were 6.
View Article and Find Full Text PDF