Publications by authors named "S Fumagalli"

Background: Atrial fibrillation (AF) is the most common arrhythmia diagnosed at an older age. AF is associated with frailty, a condition possibly justifying the higher rate of complications and mortality in aged individuals. This study was aimed at describing the characteristics correlated to frailty in older AF subjects.

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  • Risk-reducing salpingo-oophorectomy (RRSO) is recommended for women with BRCA1/2 pathogenic variants to prevent ovarian cancer, but many still refuse the surgery despite its benefits.
  • A study at a referral center in Italy analyzed 287 women, finding a high uptake rate of 96.1% for RRSO after counseling, although some women were hesitant due to fears about menopause and childbearing.
  • The study suggests that a specialized clinic with a supportive team and options for surveillance plays a crucial role in encouraging women to consider risk-reducing surgery.
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  • - The study investigates the impact of care levels at different obstetric units on maternal and perinatal outcomes during code red cesarean deliveries, which are performed when there’s a life-threatening situation for the mother or fetus.
  • - The research analyzed 168 cases from various hospitals and found that while the decision-to-delivery interval (DDI) was similar at both level-1 and level-2 hospitals, the rates of appropriate indications were higher at level-2 hospitals, although they had worse perinatal outcomes.
  • - The results indicate that while level-1 hospitals can respond as quickly as level-2 hospitals in emergencies, they have lower rates of appropriate indications for cesarean deliveries, and the level of care and the
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  • - The study explores in-hospital mortality risk factors for older patients (60+) during the COVID-19 pandemic, emphasizing the ongoing impact of COVID-19 as endemic disease, particularly for those with multiple health issues.
  • - Utilizing data from the Gerocovid-acute wards, researchers incorporated 71 variables into a machine learning platform to identify key prognostic factors affecting mortality, avoiding selection bias and enabling extensive model testing.
  • - The analysis revealed that, alongside traditional health metrics, pre-COVID-19 mobility emerged as a critical predictor of in-hospital mortality, highlighting its importance in risk assessment for older patients.
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  • Trazodone, an antidepressant often prescribed for insomnia, anxiety, and behavioral disorders, is the focus of a study aimed at understanding its prescription reasons, effectiveness, and side effects in older adults in long-term care facilities.
  • The study included feedback from 37 out of 74 participating long-term care facilities, analyzing data from 427 older adults, revealing that common reasons for prescribing trazodone included agitation, insomnia, and depression, with over 90% reporting it was effective.
  • While trazodone proved beneficial, the study identified falls as a key side effect, affecting 30% of participants, underlining the need for careful monitoring in elderly patients, especially those with dementia.
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