Publications by authors named "S Fujiki"

Brown adipose tissue (BAT) plays an important role in energy metabolism because it uses fatty acids for thermogenesis during cold exposure. Preclinical studies found that boysenberry anthocyanins (BoyACs) activate BAT. Therefore, the aim of this preliminary study was to evaluate how BoyAC intake affects BAT in humans.

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  • Paroxysmal sympathetic hyperactivity (PSH) is a condition linked to autonomic nervous system dysfunction, often seen in severe brain injuries, but non-traumatic causes like infections can also trigger it.
  • A case study discusses a 30-year-old man diagnosed with neurosyphilis who experienced abnormal symptoms like seizures and agitation, leading to a PSH diagnosis after ruling out other conditions.
  • Treatment with propranolol, gabapentin, and clonidine successfully managed his PSH symptoms, highlighting the importance of recognizing and addressing PSH early in cases of central nervous system infections.
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  • * In a subgroup analysis of 601 patients, those with anemia showed significantly fewer recurrent venous thromboembolism (VTE) cases with 12-month edoxaban treatment compared to 3 months, while no such reduction was observed in patients without anemia.
  • * Overall, 12-month edoxaban treatment was more effective in preventing thrombotic events for both anemia and no-anemia groups, with no significant difference in major bleeding risk between the two treatment durations.
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Lowering mean pulmonary arterial pressure (mPAP) without reducing cardiac output is essential in treating pulmonary hypertension (PH). Isosorbide dinitrate (ISDN) potentially achieves this in post-capillary PH but can decrease cardiac output and blood pressure (BP), especially in pre-capillary PH. However, post-capillary PH and pre-capillary PH can overlap, and their clear discrimination is difficult.

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Background: Trastuzumab has improved breast cancer (BC) prognosis and reduced anthracycline use. However, the characteristic changes of anthracycline-related cardiomyopathy (ARCM) in patients with BC remain unclear. We aimed to update our understanding of ARCM in the trastuzumab era.

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