Publications by authors named "S Franik"
Background: Klinefelter syndrome (KS) is associated with an increased risk of lower socioeconomic status and a higher risk for morbidity and mortality, which may have a significant impact on quality of life (QOL). The objective of this study is to investigate QOL in a large European cohort of men with KS.
Design: Cross-sectional multicentre study.
Phytoestrogen Treatment for Menopausal Vasomotor Symptoms after Breast Cancer.
Breast Care (Basel)
June 2023
Introduction: In breast cancer patients, menopausal symptoms are often reached earlier and in a more severe manner than in healthy women. They can dramatically reduce a patient's quality of life. Treatment for breast cancer patients remains difficult due to hormone replacement therapy being contraindicated.
View Article and Find Full Text PDFAromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.
Cochrane Database Syst Rev
September 2022
Background: Polycystic ovary syndrome (PCOS) is the most common cause of infrequent periods (oligomenorrhoea) and absence of periods (amenorrhoea). It affects about 5% to 20% of women worldwide and often leads to anovulatory infertility. Aromatase inhibitors (AIs) are a class of drugs that were introduced for ovulation induction in 2001.
View Article and Find Full Text PDFArticle Synopsis
- * A study involving 205 men with KS across six European countries found that they had significantly lower educational achievement, job rates, and income satisfaction compared to a normal male population.
- * Health issues and poor general health perceptions among men with KS contributed to their lower levels of employment and income satisfaction.
Article Synopsis
- Assisted hatching (AH) is a technique that helps embryos break out of their protective outer layer (zona pellucida) to improve implantation chances during assisted conception.
- A systematic review was conducted, including 39 randomized controlled trials (RCTs) involving 7249 women, to evaluate the effects of AH on live birth and multiple pregnancy rates.
- The evidence from these studies indicated low to very low-quality results, with significant concerns about bias and reporting issues, leading to inconclusive findings about the benefits of AH.