Resistance exercise-induced hormonal response promotes satellite cell proliferation in untrained men but not in women.

The purpose of this work was to determine the effect of resistance exercise (RE)-induced hormonal changes on the satellite cell (SC) myogenic state in response to muscle damage. Untrained men ( = 10, 22 ± 3 yr) and women ( = 9, 21 ± 4 yr) completed 2 sessions of 80 unilateral maximal eccentric knee extensions followed by either an upper body RE protocol (EX) or a 20-min rest (CON). Muscle samples were collected and analyzed for protein content of Pax7, MyoD, myogenin, cyclin D1, and p21 before (PRE), 12 h, and 24 h after the session was completed.

[Dehydroepiandrosterone metabolism by Epidermophyton floccosum].

Steroid hormones may be relevant for the fungus-host relation in dermatophytoses. In contrast to most other hosts of dermatophytes, humans are characterized by a high cutaneous concentration of the adrenal androgen dehydroepiandrosterone (DHEA) and its sulphate (DHEAS). To investigate whether the strictly anthropophilic dermatophyte Epidermophyton floccosum can metabolize this steroid hormone, cultures of E.

Human androgenic steroids affect growth of dermatophytes in vitro.

Hormonal effects on fungal growth are of particular interest to medical mycology. In the skin, androgenic steroids metabolized within pilosebaceous units may have direct effects on dermatophytes that invade hair follicles. In this study, 10(-1) to 10(2) mg 1(-1) testosterone, 5-alpha-dihydrotestosterone, dehydroepiandrosterone, androstenedione and androstanedione were used in agar dilution assays to test their effects on thallus diameters of Trichophyton rubrum, Epidermophyton floccosum, T.