[Bartonella and bartonellosis--emerging and re-emerging infections: epidemiology, clinical course, diagnosis].

Information on the epidemiology, clinic and diagnostics of bartonellosis is updated. The importance of bartonellosis lies in the fact that its main risk group embraces patients with immunodeficiencies of different origin, the number of such patients constantly growing. The diagnostics of bartonellosis is insufficiently developed and the research on Bartonella organisms, except for the trunch (Volynia) fever causative agent, is insufficient in our country.

[Bartonella and bartonellosis--emerging and re-emerging infections. Taxonomy, bacteriology, pathogenesis and genetics].

The review updates knowledge on the taxonomy, bacteriology and genetics of Bartonella as well as pathogenesis of bartonellosis. The role of Bartonella in human pathology, formerly considered to be rather modest, causes now growing anxiety. In this connection Bartonella are now believed to be the causative agents of so-called emerging and re-emerging diseases, i.

Autoimmune component in individuals during immune response to inactivated combined vaccine against Q fever.

Serum samples from 20 individuals immunized with inactivated combined vaccine (ICV) against Q fever and 10 individuals that received placebo were investigated on days 14, 21, 28 and 60 after immunization by isotope specific enzyme-linked immunosorbent assay (ELISA) for the presence of antibodies directed to human IgA, IgM and IgG, and their fragments (F(ab')2, Fab, Fc). None of the subjects that received placebo exhibited significant increase of reactivity with any of the used antigens. By contrast, the sera of immunized individuals tended to show increased autoantibody activity with diverse antigens.