Publications by authors named "S Fanucci"
Article Synopsis
- Metabolic changes in the tumour microenvironment help cancer cells survive and resist treatments, driven by inflammation from adipose (fat) tissue.
- STAT3 is identified as a key player in these metabolic changes, influencing cancer cell behavior by responding to signals from adipose tissue and other inflammatory factors.
- The review highlights how the interplay between STAT3's functions in gene regulation and mitochondrial activity supports cancer cell survival and growth, particularly in the context of breast cancer related to fat tissue.
Bioprinting advances have revolutionised drug discovery and are set to disrupt biomedical research and medical application through the development of reproducible, fine-tuned functional 3D tissues and, eventually, whole organs. This intersectional bottom-up approach of additive manufacturing requires collaboration between tissue engineers, materials chemists, software and electrical engineers and medical practitioners for the software, hardware and wetware required by this disruptive technology. This review provides a current overview of the state of the art of bioprinting and the biomaterials/bioinks required, as well as the challenges and prospects for medical application in South Africa.
View Article and Find Full Text PDF