Publications by authors named "S FERRIER"
Background: Uveal melanoma (UM) is the most common primary intraocular tumour in adults, and approximately 50% of patients will develop metastasis. Epigenetic changes are a major factor in cancer progression. We aimed to determine whether methylation profiles could be altered using a DNA methyltransferase (DNMT) inhibitor in UM cell lines.
View Article and Find Full Text PDFAlthough monotremes diverged from the therian mammal lineage approximately 187 million years ago, they retain various plesiomorphic and/or reptilian-like anatomical and physiological characteristics. This study examined the morphology of juvenile and adult female reproductive tracts across various stages of the presumptive oestrous cycle, collected opportunistically from cadaver specimens submitted to wildlife hospitals during the breeding season. In adult females, ovaries had a convoluted cortex with follicles protruding from the ovarian surface.
View Article and Find Full Text PDFArticle Synopsis
- Global biodiversity is declining, prompting businesses and society to urgently adopt new operating models, particularly the "nature positive" concept.
- Successful implementation hinges on collaboration between ecologists and businesspeople, emphasizing a shared understanding of key terms, concepts, and associated risks.
- Key aspects to consider include ecological definitions (health, abundance, diversity, resilience), financial tools for nature positive initiatives, and understanding risks, highlighting that while the concept may seem simple, managing biodiversity complexities is crucial and worthwhile.
Article Synopsis
- Natural ecosystems capture significant carbon by using biological diversity to create durable structures, like tree bark and roots.
- Current carbon sequestration models often overlook how important biodiversity is for effective carbon storage, leading to potential inaccuracies in projections.
- The loss of plant diversity due to climate and land use changes could result in significant carbon losses, reinforcing a cycle that worsens climate change, while conserving biodiversity can aid in mitigating its effects.
Based on an extensive model intercomparison, we assessed trends in biodiversity and ecosystem services from historical reconstructions and future scenarios of land-use and climate change. During the 20th century, biodiversity declined globally by 2 to 11%, as estimated by a range of indicators. Provisioning ecosystem services increased several fold, and regulating services decreased moderately.
View Article and Find Full Text PDF