One-Step Synthesis of 2-Arylquinolin-4(1)-Ones from 1-(2-Aminoaryl)-3-Arylpropan-1-Ones via Pd(II)-Catalyzed Dehydrogenative Cyclization.

In this study, we developed palladium-catalyzed dehydrogenative cyclization to transform 1-(2-aminoaryl)-3-arylpropan-1-ones into 2-arylquinolin-4(1)-ones, also known as aza-flavones which are the bioisosteres of flavones, in an atom-economic manner. This method exhibited excellent chemical compatibility with a broad substrate scope, accommodating up to 25 derivatives. Additionally, kinetic studies were performed to elucidate the reaction mechanism.

A supercritical oil extract of seeds ameliorates Huntington's disease-like symptoms and neuropathology: the potential role of anti-oxidant and anti-inflammatory effects.

Background: Huntington disease (HD), a neurodegenerative autosomal dominant disorder, is characterized by involuntary choreatic movements with cognitive and behavioral disturbances. Up to now, no therapeutic strategies are available to completely ameliorate the progression of HD. has various pharmacologic effects such as antioxidant and anti-inflammatory activities.

Feeding behavior and prey characteristics of great egrets (Ardea alba) in eco-friendly and conventional rice fields in South Korea.

Rice fields are important wildlife habitats; however, intensive agricultural practices have reduced the population of farmland birds. As a high-level consumer, the great egret (Ardea alba) serves as an indicator of the overall biodiversity of rice fields. However, little is known about the effects of farming methods on the feeding habitat selection of the great egret.

Soybean mitogen-activated protein kinase GmMPK6 enhances drought tolerance.

Soybeans are a critical crop that provides both protein and oil. In response to environmental stresses, mitogen-activated protein kinases (MPKs) play a key role in transmitting stress signals to the nucleus to initiate stress-responsive actions. Drought stress reduces plant development and productivity but the specific MPK responsible for drought stress responses has not been previously identified.

Investigation of validity and inter examiner agreement of quantitative light induced fluorescent images in diagnosing cracked teeth.

The images of the Quantitative Light induced Fluorescent (QLF) device, which provides both natural color images similar to those from intraoral cameras and fluorescent images using 405 nm light in a single shot, were evaluated for the validity and inter examiner reliability in detecting tooth cracks. QLF images of 26 cracked teeth before and after removing crack lines were taken. Two examiners assessed the QLF images before removing the crack line with natural color images, fluorescent images, and combination images showing both images simultaneously, and recorded the crack's location after observing images.