Publications by authors named "S F Pearce"

Background: Longitudinal studies of thyroid function have demonstrated differing results. It remains unclear whether changes in thyroid function affect the diagnosis of subclinical thyroid dysfunction with ageing.

Methods: Survivors of the Whickham cohort study were evaluated on two occasions between the years 2008-2012 and 2016-2019.

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Introduction: HCV antibody assays have been used to screen for HCV, but confirmation of acute infection is dependent on RNA or core antigen testing. The aim of the study was to compare the performance of five HCV test methods, including RNA testing, on a US emergency department population.

Methods: Clinical performance metrics were calculated on 708 consenting Johns Hopkins Emergency Department patients who self-reported an increased risk for HCV infection.

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Two trials were conducted to determine interactive effects between lipid source (palm oil, PO versus soybean oil, SO) and emulsifier addition (none versus glycerol monolaurate-GML) on apparent total tract digestibility (ATTD) of gross energy (GE) in broilers and growth performance in poults. In trial 1, 0.05 % GML addition had no impact on the ATTD of GE of SO but improved the ATTD of PO from 77.

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Unlabelled: Resilience in nursing medication administration practice: a systematic review with narrative synthesis.

Objective: Little is known about how nurses adapt medication administration practices to preserve safety. The capacity to adapt and respond before harm occurs has been labelled 'resilience'.

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Article Synopsis
  • The prevalence of hepatitis C virus (HCV) infection in the U.S. has risen over the past decade, despite effective treatments being available, highlighting the need for better screening methods to prevent transmission.
  • The traditional screening method relies on detecting HCV antibodies, which can take about 6 weeks to appear, potentially delaying diagnosis, especially in immunocompromised individuals; however, testing for HCV core antigen may allow for earlier and potentially cheaper detection.
  • A study evaluated the agreement between a new HCV core antigen assay and standard nucleic acid amplification testing (NAAT), showing a high concordance rate of 97.1%, suggesting that this assay could reliably detect and confirm HCV infection.
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