Publications by authors named "S F Lieske"

Countries' circularity performance and CO emissions should be addressed as a part of the UN net-zero Sustainable Development Goals (SDGs) 2030. Macro-scale circularity assessment is regarded as a helpful tool for tracking and adjusting nations' progress toward the sustainable Circular Economy (CE) and SDGs. However, practical frameworks are required to address the shortage of real-world circularity assessments at the macro level.

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Article Synopsis
  • The study investigates whether pharmacogenomic testing can improve the selection of antidepressants for patients with major depressive disorder (MDD) and lead to better treatment outcomes compared to standard care.
  • Conducted at 22 Veterans Affairs medical centers, the trial involved 1,944 patients and 676 clinicians, assessing the effectiveness of treatment guided by pharmacogenomic results over 24 weeks.
  • Results showed a significant portion of the pharmacogenomic-guided group received prescriptions with fewer drug-gene interactions, suggesting potential advantages in using such testing for choosing antidepressants in MDD treatment.
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Background: Associations between ambient temperature exposure during pregnancy and stillbirth have been reviewed and described in the literature. However, there is no existing review of environmental and epidemiologic methods applied to measure stillbirths resulting from exposure to ambient temperatures during pregnancy. The objective of this study is to systematically review published methods, data sources, and data linkage practices to characterize associations between ambient temperature and stillbirth to inform stillbirth prevention and risk management strategies.

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Reduced expression of the plasma membrane citrate transporter INDY (acronym I'm Not Dead, Yet) extends life span in lower organisms. Deletion of the mammalian Indy (mIndy) gene in rodents improves metabolism via mechanisms akin to caloric restriction, known to lower blood pressure (BP) by sympathoadrenal inhibition. We hypothesized that mIndy deletion attenuates sympathoadrenal support of BP.

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Background: Despite advances in the care of women and their babies in the past century, an estimated 1.7 million babies are born still each year throughout the world. A robust method to estimate a pregnant woman's individualized risk of late-pregnancy stillbirth is needed to inform decision-making around the timing of birth to reduce the risk of stillbirth from 35 weeks of gestation in Australia, a high-resource setting.

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