Association between socioeconomic status and the triglyceride glucose index: a cross-sectional study based on NHANES 2007-2016.

Background: The triglyceride glucose index (TyG index) is a crucial marker for assessing the risk of chronic diseases, while socioeconomic status (SES), measured by poverty income ratio (PIR) and education level, reflects an individual's social standing. Past studies have linked SES to diabetes and cardiovascular diseases, but research on its association with the TyG index is limited. This study aimed to explore the association between SES and the TyG index and assess the mediating role of BMI.

Imbalance of bladder neurohomeostasis by Myosin 5a aggravates diabetic cystopathy.

Background: Diabetic cystopathy (DCP) is linked to bladder nerve conduction disorders, with diabetes-induced neuropathy impairing nerve signal transmission and causing bladder dysfunction. Myosin 5a, vital for neuronal transport, has been linked to neurological disorders, though its role in DCP remains unclear. The objective of this study was to investigate whether Myosin 5a plays a potential regulatory role in Diabetic Cystopathy.

Button Battery Ingestion: Exploring Socioeconomic Risk Factors.

Objective: Examine the demographic and social determinants of health linked to pediatric esophageal foreign body removals, with an emphasis on button battery ingestions.

Study Design: A retrospective chart review was performed on pediatric patients who underwent operative removal of a foreign body from the esophagus (Current Procedural Terminologies [CPTs] 43215, 43194).

Setting: The study was conducted across four hospitals from November 2010 to December 2023.

Taurine supplementation alleviates asthma airway inflammation aggravated by HOCl exposure.

Environmental pollutant exposure has been demonstrated to be associated with the onset and progression of asthma. Hypochlorous acid (HOCl), as an environmental exposure-relevant chlorine-based disinfectant, its role in asthmatic airway inflammation remains unclear. Through administering HOCl in drinking water during early life and the perinatal period, we discovered that early-life HOCl drinking water exposure not only aggravated airway inflammation in asthmatic mice but also that perinatal HOCl drinking water exposure could promote airway inflammation in the offspring of asthmatic mice.

Serum IgE in the clinical features and disease outcomes of anti-interferon-γ autoantibodies syndrome.

Background: Anti-interferon-γ autoantibodies (AIGAs) syndrome is a recently recognized adult-onset immunodeficiency syndrome. Serum Immunoglobulin E (IgE) is increased in AIGAs syndrome, but the role of serum IgE levels in the clinical features and disease outcomes of AIGAs syndrome is not clear.

Methods: We retrospectively enrolled 163 patients diagnosed AIGAs syndrome with serum IgE examined at baseline from 2021 to 2024 and compared the clinical features between Group A (serum IgE level ≤ 212 IU/mL) and Group B (serum IgE level > 212 IU/mL).